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KMID : 0616620090150010075
Journal of Soonchunhyang Medical College
2009 Volume.15 No. 1 p.75 ~ p.81
The Factors Related to the Incidence of Non-Alcoholic-Fatty-Liver-Disease (NAFLD) in Obese Patients
Park Jong-Su

Yoo Byung-Wook
Oh Jung-Eun
Hong Sung-Ho
Cho Choo-Yon
Cho Yong-Jin
Abstract
Background:The incidence of the non-alcoholic-fatty-liver-disease (NAFLD) is rising in Korea. This study examines factors related to the incidence of NAFLD, as well as the incidence of diabetes, hypertension and dyslipidemia in obese patients.

Methods :A sample of 159 patients out of 893 obesity patients who received abdominal ultrasonic examinations in Soonchunhyang Hospital (Cheon An) between October and December 2004. 81 out of 159 patients were diagnosed as having fatty liver and 78 patients consisted of the control group, Fat weight, body fat, and abdominal fat, cholesterol, blood pressure and liver enzymes, fasting glucose level were measured.

Results:The average age of the study group was 45,68 and consisted of 64 males and 17 females. 31 out of the patients were in 40¡¯s. There was no significant difference between the two groups in fat weight, body fat. There was a significant difference between the two groups in BMI, diastolic blood pressure, fasting glucose, triglycerides , HDL cholesterol levels and AST and ALT. The ASTIALT ratio in the study group was 0.82, But 14 patients in the test group were diabetics, whereas 2 patients in the control group were diabetics, which indicated a significant difference between the two groups in the incidence of diabetes.

Conclusions:Factors related to the incidence of NAFLD included diastolic blood pressure, fasting glucose, total cholesterol , triglycerides, AST, ALT, and HDL cholesterol level. The study results showed a significant difference between the two groups only in the incidence of diabetes.
KEYWORD
Nonalcoholic fatty liver disease, Obesity, Related factors
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